- Increased carboxyhemoglobin and serum iron concentration as an indicator of increased red cell turnover in preeclampsia.
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Sang Heon Kim, Kwang Hee Lee, Mi Sook Kim, Young Gi Lee, Yoon Kee Park, Tae Hyung Lee, Sung Ho Lee
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Yeungnam Univ J Med. 1993;10(1):68-76. Published online June 30, 1993
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DOI: https://doi.org/10.12701/yujm.1993.10.1.68
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 Abstract
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- Pregnancy induced hypertension is multifaceted syndrome with variable involvement of several key organ systems, so sensitive and specific laboratory tests for predicting severity and prognosis. and early diagnosis of this disease are required. Because heme catabolism results in equimolar production of carboxyhemoglobin, iron and bilirubin, a concomittant rise of these parameters would provide confirmation of increased heme catabolism. Microangiopathic hemolytic anemia may occurs in severe preeclampsia, but it is not known whether increased red cell turnover - occurs with mild preeclampsia as complication. The purpose of this study was to confirm that increased heme catabolism also occurs in patients with mild preeclampsia. The analysis of data was done on 23 cases with mild preeclampsia and 35 normal pregnant women, who were admitted to Yeungnam University Hospital from October 1992 to March 1993. The results were as follows. 1. The mean antepartum serum iron concentration was significantly higher in the group with mild preeclampsia (86.5+/-6.1 microg/dl) than in the controls (53.2+/-5.3 microg/dl). 2. The mean antepartum and postpartum carboxyhemoglobin concentrations were significantly higher in the group with mild preeclampsia (antepartum : 2.55+/-0.42 mg/dl, postpartum 1.21+/-0.4 mg/dl) than the controls (antepartum : 0.61+/-0.2 mg/dl, postpartum 0.53+/-0.2 mg/dl) 3. During postpartum, carboxyhemoglobin concentration in preeclampsia reduced significantly from antepartum level, but there was no difference between antepartum and postpartum carboxyhemoglobin concentrations among controls. 4. Bilirubin concentrations were similiar in both groups
- A case of meigs' syndrome occured in pregnancy.
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Dae Hyun Cho, Sang Heon Kim, Min Whan Koh, Tae Hyung Lee, Sung Ho Lee
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Yeungnam Univ J Med. 1992;9(1):197-202. Published online June 30, 1992
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DOI: https://doi.org/10.12701/yujm.1992.9.1.197
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Abstract
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- Meigs' syndrome consists of an ovarian fibroma, or fibroma-like benign tumor, associated with fluid in both abdomen and chest. Characteristically, the ascites and hydrothorax disappeared and do not recurred following removal of the ovarian tumor. The authors presented a case of Meigs' syndrome that was cured by surgical removal of ovarian tumor and resulted in normal pregnancy outcome in 27-year-old pregnant woman with a brief review of literatures.
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Yeungnam University College of Medicine
